| Attribute | Details | |---|---| | | CLSI M22A3E | | ISBN Number | 1-56238-536-4 | | Publication Date | June 20, 2004 | | List Price | $180.00 USD (Non-member price) | | Availability | Electronic format (PDF) only; print not available | | Pages | 44 | | Edition | Third Edition | | Status | Archived (technically valid) |
Offers the PDF version with electronic download capabilities.
Adhering to CLSI guidelines is a cornerstone of laboratory excellence for several reasons: Accreditation Compliance
One of the most influential aspects of M22-A3 is its definition of . The standard argues that for certain media with a proven track record of reliability, user-performed quality control (QC) is unnecessary. This is based on:
Ensure proper storage conditions (temperature and humidity control). clsi m22a3 pdf link
Based on data from the , CLSI M22-A3 identified that certain commercially produced media have a very low, acceptable failure rate (less than or equal to 0.5%). Responsibilities for Exempt Media
Media used for susceptibility testing (unless otherwise validated under specific standards) Laboratory Responsibilities Under M22-A3
The Clinical and Laboratory Standards Institute (CLSI) publishes , titled "Quality Control for Commercially Prepared Microbiological Culture Media; Approved Standard—Third Edition." This framework outlines the criteria that streamline workflow efficiencies while strictly maintaining quality assurance protocols across clinical, research, and industrial laboratory landscapes. Core Principles and Objectives
Testing with specific ATCC control strains to ensure expected growth. | Attribute | Details | |---|---| | |
The CLSI M22-A3 standard, "Quality Control for Commercially Prepared Microbiological Culture Media," provides essential guidelines for ensuring the reliability of ready-to-use culture media, with a focus on exempting, from retesting, media with proven low failure rates. This third edition document details quality assurance roles for manufacturers and laboratories, including protocols for maintaining test strains. The official document can be purchased from the Clinical and Laboratory Standards Institute , with preview options available at the ANSI Webstore .
The document, titled "Quality Control for Commercially Prepared Microbiological Culture Media," is a critical standard used in clinical laboratories to ensure the performance and reliability of culture media. Overview of CLSI M22-A3
The document establishes a rigorous framework dividing media into distinct categories based on historical failure rates and preparation complexity. User vs. Manufacturer Responsibilities
In the realm of clinical microbiology, the reliability of diagnostic results relies heavily on the quality of the media used to grow microorganisms. The provides essential guidelines to ensure this quality. One of the cornerstone documents for laboratories sourcing pre-made media is CLSI M22-A3 , titled "Quality Control for Commercially Prepared Microbiological Culture Media; Approved Standard—Third Edition". This is based on: Ensure proper storage conditions
CLSI members can save up to 70% off the list price when purchasing through their membership.
Navigating CLSI M22-A3: Standards for Quality Control of Microbiological Culture Media
The American National Standards Institute (ANSI) also provides the standard for purchase as an official distributor.
for antimicrobial susceptibility testing, the fundamental principles of media quality control found in M22-A3 remain the backbone of reliable diagnostics. Following these standards helps prevent erroneous results that could negatively affect patient care. Are you updating your lab's Quality Control plan?
CLSI and its distributors enforce copyright protection to maintain the integrity and financial viability of their standards development process. The PDFs sold by platforms like Accuris are typically "secured PDFs." This means you may need to install a free plugin (such as FileOpen) to view the document. These security measures generally allow you to text but often prohibit copying and pasting text or sharing the file with unauthorized users.